doi: 10.1126/science.877582.
Structure of a molluscan cardioexcitatory neuropeptide
- PMID: 877582
- DOI: 10.1126/science.877582
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Structure of a molluscan cardioexcitatory neuropeptide
Science.
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Abstract
A cardioexcitatory substance from ganglia of the clam Macrocallista nimbosa, formerly designated peak C, is the tetrapeptide amide Phe-Met-Arg-Phe-NH2. Its structure was determined by the combined use of Edman dansyl degradation and tryptic digestion. The structure was confirmed by synthesis. This neuropeptide is active at about 10(-8)M when assayed on molluscan muscle.
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