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. 1996 Jan-Mar;38(1):39-43.

Experimental immunization of hamsters with an EDTA extract of Leptospira interrogans, serovar icterohaemorrhagiae

L T de Queiroz-Leite  1 , M Resende, N Ramos-Vieira M das, M Cota-Koury
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  • PMID: 8783904

Experimental immunization of hamsters with an EDTA extract of Leptospira interrogans, serovar icterohaemorrhagiae

L T de Queiroz-Leite et al. Rev Latinoam Microbiol. 1996 Jan-Mar.

Abstract

The EDTA extract was prepared from the Leptospira interrogans serovar icterohaemorrhagiae. When inoculated subcutaneously in hamsters it conferred protection from challenge with virulent leptospires with a low dose (10 micrograms/ml) and low agglutinating antibody (40). The protection of animals obtained by the EDTA extract opens up the perspective of its use as a component of a vaccine for the control of leptospirosis.

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