doi: 10.1038/nsb0996-747.
The hairpin stack fold, a novel protein architecture for a new family of protein growth factors
- PMID: 8784346
- DOI: 10.1038/nsb0996-747
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The hairpin stack fold, a novel protein architecture for a new family of protein growth factors
Nat Struct Biol.
1996 Sep.
Abstract
The granulin/epithelin protein motif has an unusual structure consisting of a parallel stack of beta-hairpins stapled together by six disulphide bonds. The new structure also contains a folding subdomain shared by small toxins, protease inhibitors as well as the EGF-like protein modules.
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