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Case Reports
. 1996 May;6(3):151-4.
doi: 10.1016/0960-8966(96)00008-9.

HTLV-1 polymyositis

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Case Reports

HTLV-1 polymyositis

C J Caldwell et al. Neuromuscul Disord. 1996 May.

Abstract

The case is described of an HTLV-1 seropositive Jamaican woman who presented with signs and symptoms of polymyositis and myelopathy. A muscle biopsy showed features of myositis with a mononuclear inflammatory infiltrate, variation in fibre size and evidence of regeneration. Immunocytochemistry showed the mononuclear cells were composed of macrophages and T-lymphocytes suggesting a cell-mediated response. Multiplex PCR demonstrated the presence of the HTLV-1 tax gene within the muscle.

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