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. 1995 Dec 29;202(1-2):37-40.
doi: 10.1016/0304-3940(95)12204-4.

Adrenomedullin-immunoreactive neurons in the paraventricular and supraoptic nuclei of the rat

Y Ueta  1 , K Kitamura, T Isse, I Shibuya, N Kabashima, S Yamamoto, K Kangawa, H Matsuo, T Eto, H Yamashita
Affiliations

Adrenomedullin-immunoreactive neurons in the paraventricular and supraoptic nuclei of the rat

Y Ueta et al. Neurosci Lett. .

Abstract

The existence of adrenomedullin (AM) in the rat hypothalamus was examined by immunohistochemistry. AM-immunoreactive neurons were found in the supraoptic nucleus (SON) and in the magnocellular parts of the paraventricular nucleus (PVN). The co-existence of AM-, oxytocin- and/or vasopressin-immunoreactivity was identified in the same neurons in the hypothalamus. The results suggest that the AM may play a role in neurotransmission or in cardiovascular control with neurohypophyseal hormones.

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