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. 1996 Jan;40(1):221-4.
doi: 10.1128/AAC.40.1.221.

Characterization of the plasmidic beta-lactamase CMY-2, which is responsible for cephamycin resistance

A Bauernfeind  1 , I Stemplinger, R Jungwirth, H Giamarellou
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Characterization of the plasmidic beta-lactamase CMY-2, which is responsible for cephamycin resistance

A Bauernfeind et al. Antimicrob Agents Chemother. 1996 Jan.

Abstract

The phenotype of Klebsiella pneumoniae HEL-1 indicates a plasmidic cephamycinase gene (blaCMY-2). Its sequence shows one open reading frame coding for a protein of 381 amino acids. CMY-2 is classified as class C beta-lactamase that is closely related to the plasmidic enzymes BIL-1 and LAT-1 and the chromosomal AmpC of Citrobacter freundii. The blaCMY-2 gene possibly was translocated onto a plasmid of C. freundii which spread to K. pneumoniae.

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