Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1996 Jan;40(1):257-9.
doi: 10.1128/AAC.40.1.257.

Penicillin tolerance and modification of lipoteichoic acid associated with expression of vancomycin resistance in VanB-type Enterococcus faecium D366

L Gutmann  1 , S Al-Obeid, D Billot-Klein, E Ebnet, W Fischer
Affiliations

Penicillin tolerance and modification of lipoteichoic acid associated with expression of vancomycin resistance in VanB-type Enterococcus faecium D366

L Gutmann et al. Antimicrob Agents Chemother. 1996 Jan.

Abstract

Induction of vancomycin resistance in Enterococcus faecium D366, which exhibits a VanB-type resistance, as well as its constitutive expression in MT9, a derivative of D366, was associated with penicillin tolerance as shown by decreased lysis and killing of the cells. This phenomenon was linked neither to decreased expression of the different autolysins nor to their decreased lytic activity on the different cell walls. The only change observed was that almost twice the normal amount of D-alanine was attached to the lipoteichoic acid.

PubMed Disclaimer

References

    1. Antimicrob Agents Chemother. 1991 Apr;35(4):776-9 - PubMed
    1. Antimicrob Agents Chemother. 1990 Oct;34(10):1901-7 - PubMed
    1. Eur J Biochem. 1991 Dec 18;202(3):1269-74 - PubMed
    1. FEMS Microbiol Lett. 1992 Feb 1;70(1):79-84 - PubMed
    1. Antimicrob Agents Chemother. 1992 Jan;36(1):77-80 - PubMed

Publication types

MeSH terms