Protein adsorption on solid surfaces
- PMID: 8791316
- PMCID: PMC3262180
- DOI: 10.1016/s0958-1669(96)80098-x
Protein adsorption on solid surfaces
Abstract
The research field of protein adsorption on surfaces appears to be as popular as ever. In the past year, several hundred published papers tackled problems ranging from fundamental aspects of protein surface interactions to applied problems of surface blood compatibility and protein surface immobilization. Although some parts of the protein adsorption process, such as kinetics and equilibrium interactions, can be accurately predicted, other aspects, such as the extent and the rate of protein conformational change, are still somewhat uncertain. The whole field is ripe for a comprehensive theory on protein adsorption.
References
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- Horbett TA, Brash JL, editors. Proteins at Interfaces II: Fundamentals and Applications. Washington, DC: American Chemical Society; 1995. A collection of papers presented at the American Chemical Society Symposium ‘Proteins at Interfaces’ held in San Diego, April 1994. The book provides a cross-section of the whole field, including modem experimental methods, competitive adsorption from multiprotein systems, protein conformational changes and surface chemistry effects on protein adsorption.
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- Haynes CA, Norde W. Globular proteins at solid/liquid interfaces. Colloids Surfaces [B] 1994;2:517–566. A comprehensive overview on the driving forces involved in protein adsorption. The basic physical processes determining the conformation of a protein and its interaction with interfaces are evaluated using a thermodynamic approach.
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- Ramsden JJ. Puzzles and paradoxes in protein adsorption. Chem Soc Rev. 1995;24:73–78.
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- Vroman L. Blood. Garden City, New York: The Natural History Press; 1968.
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- Hendrickson WA, Wüthrich K, editors. Macromolecular Structures 1994. London: Current Biology Ltd; 1994. An annually published catalog of solved protein structures. Although somewhat expensive, the series is a valuable resource for any laboratory that is seriously involved in protein work. Other annual catalogs in this series are available from 1991.
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