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. 1996 Aug;59(8):786-8.
doi: 10.1021/np9602574.

Tolypodiol, an antiinflammatory diterpenoid from the cyanobacterium Tolypothrix nodosa

M R Prinsep  1 , R A Thomson, M L West, B L Wylie
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Tolypodiol, an antiinflammatory diterpenoid from the cyanobacterium Tolypothrix nodosa

M R Prinsep et al. J Nat Prod. 1996 Aug.

Abstract

A new diterpenoid, tolypodiol (1), has been isolated from the terrestrial cyanobacterium Tolypothrix nodosa (HT-58-2) and identified by NMR and mass spectral analysis. The monoacetate derivative 2 was prepared. Tolypodiol (1) and its monoacetate derivative 2 show potent antiinflammatory activity in the mouse ear edema assay.

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