Review
doi: 10.1016/s0959-440x(96)80113-8.
Porins: general to specific, native to engineered passive pores
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- PMID: 8794162
- DOI: 10.1016/s0959-440x(96)80113-8
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Review
Porins: general to specific, native to engineered passive pores
Curr Opin Struct Biol.
1996 Aug.
Abstract
Several porins from bacterial outer membranes have been crystallized and analyzed by X-ray diffraction, yielding a consistent picture of these membrane-channel proteins. The structures of general and specific channels are in agreement with electrophysiological, diffusional and biochemical data, and provide a starting point for the engineering of other passive membrane pores or porins with new selectivities.
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