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Review
. 1996 Aug;6(4):485-90.
doi: 10.1016/s0959-440x(96)80113-8.

Porins: general to specific, native to engineered passive pores

G E Schulz  1
Affiliations
Review

Porins: general to specific, native to engineered passive pores

G E Schulz. Curr Opin Struct Biol. 1996 Aug.

Abstract

Several porins from bacterial outer membranes have been crystallized and analyzed by X-ray diffraction, yielding a consistent picture of these membrane-channel proteins. The structures of general and specific channels are in agreement with electrophysiological, diffusional and biochemical data, and provide a starting point for the engineering of other passive membrane pores or porins with new selectivities.

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