Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1977 Apr 15;164(1):179-83.
doi: 10.1042/bj1640179.

Heterogeneity of proteoglycans in developing chick limb cartilage

N S Vasan, J W Lash

Heterogeneity of proteoglycans in developing chick limb cartilage

N S Vasan et al. Biochem J. .

Abstract

Proteoglycan heterogeneity was studied during the maturation of embryonic-chick limb cartilage in vivo. The results suggest that during the differentiation of limb-bud cartilage the aggregated forms of proteoglycans increase between stages 24 and 35, whereas the non-aggregated or monomeric forms decrease. Only one link protein is found in stage-24 limb buds, whereas two are present at stage 35. Evidence suggests that the synthesis of link proteins may be a regulatory factor in limb chondrogenesis.

PubMed Disclaimer

References

    1. Biochim Biophys Acta. 1975 Jan 30;379(1):282-94 - PubMed
    1. Nature. 1970 Aug 15;227(5259):680-5 - PubMed
    1. J Biol Chem. 1976 Jun 10;251(11):3511-9 - PubMed
    1. Dev Biol. 1965 Apr;11:155-68 - PubMed
    1. J Biol Chem. 1974 Jul 10;249(13):4232-41 - PubMed

Publication types