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. 1977 Apr 15;164(1):281-2.
doi: 10.1042/bj1640281.

Cellular transport of lysosomal enzymes: an alternative hypothesis

J B Lloyd

Cellular transport of lysosomal enzymes: an alternative hypothesis

J B Lloyd. Biochem J. .

Abstract

Hickman & Neufeld [(1972) Biochem, Biophys. Res. Commun. 49, 992-999] have proposed that lysosomal enzymes reach the lysosomes by means of exocytosis and subsequent pinocytic reincorporation. The results leading to this conclusion are re-assessed and an alternative explanation is advanced that relates to the necessity for membrane recycling in endocytic cells.

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