Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1979 Apr;6(4):1547-56.
doi: 10.1093/nar/6.4.1547.

Effect of toyocamycin on the synthesis of the 70S RNA of a murine retrovirus

C J Larsen, M Mauchauffé, R Hamelin, L Péraudeau, L Fedele, A Tavitian
Free PMC article

Effect of toyocamycin on the synthesis of the 70S RNA of a murine retrovirus

C J Larsen et al. Nucleic Acids Res. 1979 Apr.
Free PMC article

Abstract

The murine Eveline cell line chronically infected by Friend virus was treated with Toyocamycin (TMC), an adenosin analog and the virions released in the presence of the drug were examined for their RNA. It was found that 70S RNA which was synthesized incorporated Toyocamycin. However, its subunit structure and its poly (A) content were apparently preserved. This incorporation may explain loss of endogenous reverse transcriptase activity.

PubMed Disclaimer

Similar articles

See all similar articles

References

    1. J Virol. 1975 Aug;16(2):397-411 - PubMed
    1. Virology. 1973 Aug;54(2):552-6 - PubMed
    1. Proc Natl Acad Sci U S A. 1974 Mar;71(3):755-9 - PubMed
    1. Virology. 1974 Sep;61(1):100-11 - PubMed
    1. Cancer Res. 1970 Mar;30(3):753-62 - PubMed