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Comparative Study
. 1996 Jul-Aug;42(4):235-9.
doi: 10.1159/000239449.

The comparative in vitro activity of clinafloxacin and other antimicrobials against vancomycin-susceptible and vancomycin-resistant enterococci

G S Itokazu  1 , C Nathan, R Hariharan, J R Kostman, S A Kabins, R A Weinstein
Affiliations
Comparative Study

The comparative in vitro activity of clinafloxacin and other antimicrobials against vancomycin-susceptible and vancomycin-resistant enterococci

G S Itokazu et al. Chemotherapy. 1996 Jul-Aug.

Abstract

The susceptibilities of 50 unique vancomycin-susceptible (n = 15) and vancomycin-resistant (n = 35) enterococci to 6 antimicrobials were compared. Teicoplanin was consistently the most active agent for all strains. Ampicillin and imipenem were active primarily for vancomycin-sensitive Enterococcus faecalis. Clinafloxacin and ciprofloxacin showed poorer activity compared to prior studies, suggesting that the emergence of quinolone resistance is now occurring in enterococci.

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