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Review
. 1996 Aug 1;6(8):962-4.
doi: 10.1016/s0960-9822(02)00639-5.

Keeping the centrosome cycle on track. Genome stability

M Winey  1
Affiliations
Free article
Review

Keeping the centrosome cycle on track. Genome stability

M Winey. Curr Biol. .
Free article

Abstract

The protein kinase Mps1 and p53 both function in centrosome duplication and the spindle cell-cycle checkpoint. Defects in these functions can be potent sources of genomic instability by allowing mitosis to proceed with aberrant mitotic spindles.

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