Closing the gap on DNA ligase
- PMID: 8805556
- DOI: 10.1016/s0969-2126(96)00070-6
Closing the gap on DNA ligase
Abstract
The crystal structure of T7 DNA ligase complexed with ATP illuminates the mechanism of covalent catalysis by a superfamily of nucleotidyl transferases that includes the ATP-dependent polynucleotide ligases and the GTP-dependent mRNA capping enzymes.
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