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. 1979 Mar;31(2):116-24.

Genetic polymorphism of the A subunit of human coagulation factor XIII

P G Board

Genetic polymorphism of the A subunit of human coagulation factor XIII

P G Board. Am J Hum Genet. 1979 Mar.

Abstract

Utilizing a fluorescent technique for the localization of transglutaminase activity after electrophoresis on thin layer agarose gels, we observed a new polymorphism of coagulation factor XIII in both platelets and plasma. The electrophoretic pattern was that of a dimeric protein. Homozygotes gave a single band, while heterozygotes presented a three banded pattern. The polymorphism was found to be due to variation of the A subunit. Data from Australian blood donors indicate that the A subunit of factor XIII has an autosomal locus.

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