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Review
. 1996 Mar;17(3):120-6.
doi: 10.1016/0167-5699(96)80603-7.

The role of host immune responses in determining the outcome of HIV infection

M Westby  1 , F Manca, A G Dalgleish
Affiliations
Review

The role of host immune responses in determining the outcome of HIV infection

M Westby et al. Immunol Today. 1996 Mar.

Abstract

The progression of disease following infection with human immunodeficiency virus (HIV) correlates with an activated immune system and would appear to depend to some degree on the immunogenetics of the host. Here, Michael Westby, Fabrizio Manca and Angus Dalgleish discuss the evidence for HLA determination of clinical outcome and the potential implications of a restricted T-cell receptor repertoire for pathogenesis.

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