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Review
. 1996 Mar;17(3):138-46.
doi: 10.1016/0167-5699(96)80606-2.

The expanding universe of T-cell subsets: Th1, Th2 and more

T R Mosmann  1 , S Sad
Affiliations
Review

The expanding universe of T-cell subsets: Th1, Th2 and more

T R Mosmann et al. Immunol Today. 1996 Mar.

Abstract

Since their discovery nearly ten years ago, T helper 1 (Th1) and Th2 subsets have been implicated in the regulation of many immune responses. In this article, Tim Mosmann and Subash Sad discuss the increasing number of T-cell subsets defined by cytokine patterns; the differentiation pathways of CD4+ and CD8+ T cells; the contribution of other cell types to these patterns; and the cytokine interactions during infection and pregnancy.

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Comment in

  • B-cell help by Tc2 cells.
    Paganelli R, Scala E, Aiuti F, Fiorilli M. Paganelli R, et al. Immunol Today. 1998 Mar;19(3):142. doi: 10.1016/s0167-5699(97)01198-5. Immunol Today. 1998. PMID: 9540274 No abstract available.

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