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. 1977;9(3):313-6.

[Effect of batrachotoxin on the selectivity of sodium channels in the membrane of a myelinated nerve fiber]

[Article in Russian]
S V Revenko, B I Khodorov
  • PMID: 882194

[Effect of batrachotoxin on the selectivity of sodium channels in the membrane of a myelinated nerve fiber]

[Article in Russian]
S V Revenko et al. Neirofiziologiia. 1977.

Abstract

Ionic currents under voltage clamp conditions were studied in the Ranvier node treated with batrachotoxin (5-10(-6)--10(-5) M). Ionic permeability ratios were measured from zero-current potential. The permeability sequence for modified (noninactivating) Na channels was: Tl greater than NH4 greater than Na approximately Li greater than K greater than guanidinum greater than Rb greater than Ca greater than Cs greater than methylamine. Deviation from the "independence relation" in modified channels for It1 was decreased.

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