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. 1996 Jan;15(1):34-7.
doi: 10.1002/(SICI)1098-2264(199601)15:1<34::AID-GCC5>3.0.CO;2-5.

Lymphoid involvement in a patient with acute myeloid leukemia: a direct phenotypic and genotypic study of single cells

W El-Rifai  1 , M L Larramendy, T Ruutu, S Knuutila
Affiliations

Lymphoid involvement in a patient with acute myeloid leukemia: a direct phenotypic and genotypic study of single cells

W El-Rifai et al. Genes Chromosomes Cancer. 1996 Jan.

Abstract

Lymphoid involvement in acute myeloid leukemia (AML) was studied using the morphology-antibody-chromosome (MAC) combination technique in one patient. The chromosomal aberration, trisomy 8, was demonstrated in AML blasts, glycophorin A-positive erythroblasts, and CD3- and CD20/22-positive small lymphocytes. This suggests that in this patient even lymphocytes belonged to the leukemic clone.

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