[Prognostic value of the level of glucocorticoids and androgens in lung cancer patients]

Abstract

Under study was the excretion of 17-OCS and 17-KS in 2 male groups operated upon for lung cancer. The first group comprised 25 patients with the postoperative survival for less than a year. The second group-28 patients, whose survival was over 5 years postoperatively. In terms of 17-OCS excretion both groups were found to be identical: the level of 17OCS in them was normal. The excretion of 17-KS in patients of both groups proved to be considerably lower than normal values. However, in patients of the second group the level of 17-KS was higher, compared with the first group, mainly on account of androsterone. Thus, the balance of steroid hormones of glucocorticoid and androgenic series as well as the correlation between them may serve as a criterion of the prognosis for operated lung cancer patients.