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Comparative Study
. 1977 Jun;83(6):669-70.

[Transformation of mitochondrial monoaminoxidases types A and B]

[Article in Russian]
K K Shatemirova, I V Vervkina, V Z Gorkin
  • PMID: 884293
Comparative Study

[Transformation of mitochondrial monoaminoxidases types A and B]

[Article in Russian]
K K Shatemirova et al. Biull Eksp Biol Med. 1977 Jun.

Abstract

Chlorgyline, a selective monoamine oxidase (MAO) of the A type inhibitor, contrary to deprenil--MAO of the B type inhibitor, prevented the appearance in the rat liver mitochondrial membrane fragments incubated under aerobic conditions of qualitatively new properties to deaminate histamine or AMP. Apparently the MAO of A type but not of B type underwent a qualitative alteration (transformation) of catalytic properties under conditions favourable for partial oxidation of SH-groups.

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