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. 1996 Sep 30;394(2):191-5.
doi: 10.1016/0014-5793(96)00951-9.

A molecular model for human Big-Endothelin-1 (Big ET-1)

H Peto  1 , R Corder, R W Janes, B A Wallace
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Free article

A molecular model for human Big-Endothelin-1 (Big ET-1)

H Peto et al. FEBS Lett. .
Free article

Abstract

A molecular model has been developed for human Big Endothelin-1, which is the immediate precursor to the potent vasoconstrictor polypeptide endothelin-1 and the target of the highly specific endothelin converting enzyme. This model is produced by a threading algorithm protocol and is consistent with all the currently available structural and biochemical data for this molecule.

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