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Review
. 1996 Feb;12(2):58-62.
doi: 10.1016/0168-9525(96)81401-6.

Deviant nucleosomes: the functional specialization of chromatin

A P Wolffe  1 , D Pruss
Affiliations
Review

Deviant nucleosomes: the functional specialization of chromatin

A P Wolffe et al. Trends Genet. 1996 Feb.

Abstract

Regulatory proteins exist with strong sequence and structural similarities to the histone proteins. Molecular genetic and cell biological analyses suggest that these proteins are localized at particular sites within the chromosome. Their assembly into nucleosomal structures confers specialized functions to individual chromosomal domains.

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