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Review
. 1996 Jun;27(4):607-11.
doi: 10.1016/0306-3623(95)00125-5.

Calcitonin gene-related peptide: vasoactive effects and potential therapeutic role

S D Brain  1 , H Cambridge
Affiliations
Review

Calcitonin gene-related peptide: vasoactive effects and potential therapeutic role

S D Brain et al. Gen Pharmacol. 1996 Jun.

Abstract

1. The cardiovascular biology of calcitonin gene-related peptide (CGRP) and the structurally related peptides amylin and adrenomedullin are briefly reviewed. 2. CGRP is a potent and long-lasting vasodilator; its possible role in disease, and the therapeutic potential of CGRP receptor agonists and antagonists is discussed.

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