Localized bullous pemphigoid of the vulva

Abstract

I report a 78-year-old female patient with multiple erosive and erythematous inflammatory lesions of the vulva of seven months duration. She was diagnosed as bullous pemphigoid based on the following findings: subepidermal blister in the histological examination, linear deposition of IgG and C3 at the basement membrane zone on direct immunofluorescence studies, and positive IgG deposition on the epidermal side of saline-split normal skin on the indirect immunofluorescence study.