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. 1996 Oct;7(10):758-66.
doi: 10.1007/s003359900227.

A radiation hybrid map spanning the entire human X chromosome integrating YACs, genes, and STS markers

J Kumlien  1 , A Grigoriev, H Roest Crollius, M Ross, P N Goodfellow, H Lehrach
Affiliations

A radiation hybrid map spanning the entire human X chromosome integrating YACs, genes, and STS markers

J Kumlien et al. Mamm Genome. 1996 Oct.

Abstract

We present a radiation hybrid (RH) map of human Chromosome (Chr) X, using 50 markers on 72 radiation hybrids. The markers, obtained from the consensus map, form a grid spanning the entire chromosome. To check the RH map, the marker order was determined by analysis of presence or absence of retained human DNA fragments in the RHs; the comparison with the consensus showed a similar order. Any STSs, microsatellites, genes, and clones can be positioned and ordered relative to the marker grid. This approach integrates genetic, physical, and large-scale clone mapping and is used to link YAC contigs containing data from various experimental sources.

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References

    1. Cold Spring Harb Symp Quant Biol. 1993;58:349-55 - PubMed
    1. Trends Genet. 1993 Oct;9(10):352-6 - PubMed
    1. Genomics. 1995 Jul 20;28(2):315-27 - PubMed
    1. Somat Cell Mol Genet. 1992 Jan;18(1):33-44 - PubMed
    1. Am J Hum Genet. 1991 Dec;49(6):1174-88 - PubMed

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