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. 1977 Jul 26;37(3):271-8.
doi: 10.1007/BF00393608.

The human PGM-2 and its chromosomal localization in man-mouse hybrids

L M Wijnen, K H Grzeschik, P L Pearson, P Meera Khan

The human PGM-2 and its chromosomal localization in man-mouse hybrids

L M Wijnen et al. Hum Genet. .

Abstract

A detailed procedure is described for a rapid detection of phosphoglucomutase-2(=phosphopentomutase;PGM-2) on Cellogel following electrophoresis of extracts of human red blood cells and other tissues, including cultured fibroblasts and various types of primate-rodent somatic hybrid cells. The present study indicated that there is only one locus for phosphopentomutase in man. The data from a selected panel of 20 independent clones of man-mouse somatic cell hybrids, investigated for the presence of human chromosomes and for the presence or absence of human PGM-2 favored the assignment of the human PGM-2 locus to chromosome 4.

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