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. 1977;54(6):553-9.
doi: 10.1159/000231876.

The antigens of pigeon breeder's disease. II. Isolation and characterization of antigen PDE1

T H Tebo, W W Fredricks, R C Roberts

The antigens of pigeon breeder's disease. II. Isolation and characterization of antigen PDE1

T H Tebo et al. Int Arch Allergy Appl Immunol. 1977.

Abstract

Antigen PDE1 was purified from pigeon dropping extracts by chromatography on DEAE-cellulose and Bio-Gel A-1.5. It was characterized as a glycoprotein, containing 88% protein and 12% carbohydrate, with a molecular weight of approximately 200,000. PDE1 appears to be derived from pigeon intestinal IgA, showing the typical immunoglobulin structure of heavy and light chains. This antigen represents about 24% of the dry weight of the unfractionated pigeon dropping extract.

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