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Clinical Trial
. 1996 Apr;19(4):215-8.
doi: 10.1007/BF03349870.

Impairment of granulation tissue formation after menopause

R Gniadecki  1 , B Wyrwas, A Kabala, J Matecka
Affiliations
Clinical Trial

Impairment of granulation tissue formation after menopause

R Gniadecki et al. J Endocrinol Invest. 1996 Apr.

Abstract

Formation of connective tissue is an essential step in the process of wound healing. After menopause an atrophy of connective tissues in skin, bone, and reproductive organs takes place. Using a dead-space wound healing model we measured collagen synthesis and deposition, and cell replication in the granulation tissue of 18 premenopausal and 23 peri- and postmenopausal women not receiving any hormonal therapy. In the postmenopausal group collagen synthesis and deposition and cell number in the granulation tissue were diminished. These results document the impairment of the granulation tissue formation after menopause.

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References

    1. Br J Obstet Gynaecol. 1987 Feb;94(2):126-9 - PubMed
    1. Fertil Steril. 1987 Nov;48(5):866-72 - PubMed
    1. Obstet Gynecol. 1987 Oct;70(4):538-41 - PubMed
    1. Prog Clin Biol Res. 1989;320:121-35 - PubMed
    1. Br J Surg. 1987 Apr;74(4):320-3 - PubMed

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