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. 1996 Aug;21(4):477-80.
doi: 10.1093/chemse/21.4.477.

Pharmacokinetic studies of the fragrance compound 1,8-cineol in humans during inhalation

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Pharmacokinetic studies of the fragrance compound 1,8-cineol in humans during inhalation

W Jäger et al. Chem Senses. 1996 Aug.

Abstract

The present study was undertaken to investigate the pharmacokinetics of 1,8-cineol in human subjects during prolonged inhalation. The results showed that 1,8-cineol is well absorbed from breathing air, with a peak plasma concentration after approximately 18 min. The elimination of this fragrance compound from the blood is biphasic, with a mean distribution half-life of 6.7 min and an elimination half-life of 104.6 min.

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