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. 1995 Sep-Oct;47(5):461-3.

Inhibitory effect of neuropeptide y on epileptiform activity in the frontal cortex and hippocampus in vitro

M Bijak  1
Affiliations
  • PMID: 8868141

Inhibitory effect of neuropeptide y on epileptiform activity in the frontal cortex and hippocampus in vitro

M Bijak. Pol J Pharmacol. 1995 Sep-Oct.

Abstract

The effect of neuropeptide Y on spontaneous epileptiform discharges was studied in cortical and hippocampal slices using an extracellular recording. Epileptiform activity which was induced by superfusion of slices with Mg(2+)-free medium was attenuated by neuropeptide Y (0.5 microM) in both the frontal cortex and hippocampal CA1 pyramidal cells.

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