Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 1996 Sep;21(9):338-42.

TAFs mediate transcriptional activation and promoter selectivity

C P Verrijzer  1 , R Tjian
Affiliations
  • PMID: 8870497
Review

TAFs mediate transcriptional activation and promoter selectivity

C P Verrijzer et al. Trends Biochem Sci. 1996 Sep.

Abstract

The TATA-binding protein (TBP)-associated factors (TAFs) of TFIID play a central role in RNA polymerase II transcriptional regulation. Some TAFs can function as co-activators that mediate the activation signal from enhancer-bound regulators. In addition, interactions between selected TAFs and core elements direct promoter selectivity by RNA polymerase II.

PubMed Disclaimer

Comment in

Publication types

LinkOut - more resources