doi: 10.1016/0165-3806(96)00087-9.
Ontogenetic development of the response to anandamide and delta 9-tetrahydrocannabinol in mice
Affiliations
- PMID: 8873985
- DOI: 10.1016/0165-3806(96)00087-9
Item in Clipboard
Ontogenetic development of the response to anandamide and delta 9-tetrahydrocannabinol in mice
Brain Res Dev Brain Res.
.
Abstract
We studied the ontogenetic response to cannabinoid receptor ligands by measuring motor activity and analgesia in response to anandamide or delta 9-THC from day 6 of age. No response to anandamide was observed up to the age of weaning (day 23), while a nonsignificant response to delta 9-THC was observed starting between days 15 and 20. This is compatible with observations that children respond to the antiemetic effects of THC without psychotropic side effects.
Similar articles
-
Dynorphin B and spinal analgesia: induction of antinociception by the cannabinoids CP55,940, Delta(9)-THC and anandamide.Brain Res. 2000 Feb 28;857(1-2):337-42. doi: 10.1016/s0006-8993(00)01981-8. Brain Res. 2000. PMID: 10700588
-
Characterization of anandamide-induced tolerance: comparison to delta 9-THC-induced interactions with dynorphinergic systems.Drug Alcohol Depend. 1997 Apr 14;45(1-2):39-45. doi: 10.1016/s0376-8716(97)01342-2. Drug Alcohol Depend. 1997. PMID: 9179505
-
The endogenous cannabinoid receptor ligand, anandamide, inhibits the motor behavior: role of nigrostriatal dopaminergic neurons.Life Sci. 1995;56(23-24):2033-40. doi: 10.1016/0024-3205(95)00186-a. Life Sci. 1995. PMID: 7776829
-
Cannabimimetic fatty acid derivatives: the anandamide family and other endocannabinoids.Curr Med Chem. 1999 Aug;6(8):721-44. Curr Med Chem. 1999. PMID: 10469888 Review.
-
[Cannabinoids in the control of pain].Recenti Prog Med. 2008 Dec;99(12):616-24. Recenti Prog Med. 2008. PMID: 19388223 Review. Italian.
Cited by
-
Influence of prenatal cannabinoid exposure on early development and beyond.Adv Drug Alcohol Res. 2023 Feb 28;3:10981. doi: 10.3389/adar.2023.10981. eCollection 2023. Adv Drug Alcohol Res. 2023. PMID: 38389825 Free PMC article. Review.
-
Neurodevelopmental liabilities of substance abuse.Neurotox Res. 2002 Jun;4(4):267-79. doi: 10.1080/1029842021000010857. Neurotox Res. 2002. PMID: 12829418
-
Short- and long-term cognitive effects of chronic cannabinoids administration in late-adolescence rats.PLoS One. 2012;7(2):e31731. doi: 10.1371/journal.pone.0031731. Epub 2012 Feb 13. PLoS One. 2012. PMID: 22348124 Free PMC article.
-
Neurobiological processes in adolescent addictive disorders.Am J Addict. 2008 Jan-Feb;17(1):6-23. doi: 10.1080/10550490701756146. Am J Addict. 2008. PMID: 18214718 Free PMC article. Review.
-
Perinatal delta-9-tetrahydrocannabinol exposure disrupts social and open field behavior in adult male rats.Neurotoxicol Teratol. 2008 May-Jun;30(3):213-9. doi: 10.1016/j.ntt.2007.12.007. Epub 2007 Dec 31. Neurotoxicol Teratol. 2008. PMID: 18272327 Free PMC article.
Publication types
MeSH terms
Substances
Grants and funding
LinkOut - more resources
Full Text Sources
Medical
