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. 1996 Sep;71(3):1335-45.
doi: 10.1016/S0006-3495(96)79333-5.

A biophysical model for defibrillation of cardiac tissue

J P Keener  1 , A V Panfilov
Affiliations

A biophysical model for defibrillation of cardiac tissue

J P Keener et al. Biophys J. 1996 Sep.

Abstract

We propose a new model for electrical activity of cardiac tissue that incorporates the effects of cellular microstructure. As such, this model provides insight into the mechanism of direct stimulation and defibrillation of cardiac tissue after injection of large currents. To illustrate the usefulness of the model, numerical stimulations are used to show the difference between successful and unsuccessful defibrillation of large pieces of tissue.

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References

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