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. 1977 Aug 26;197(4306):908-10.
doi: 10.1126/science.887930.

Reye's syndrome: patient serum alters mitochondrial function and morphology in vitro

Reye's syndrome: patient serum alters mitochondrial function and morphology in vitro

J R Aprille. Science. .

Abstract

A direct relationship between a putative Reye's syndrome "serum factor" and generalized mitochondrial damage has been demonstrated in vitro. The clinical features of Reye's syndrome may be secondary to disrupted mitochondrial structure and a consequent impairment of energy-linked functions involving many organs.

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