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Case Reports
. 1996 Sep;9(9):935-7.
doi: 10.1016/s0895-7061(96)00117-3.

Elevated endothelin-1 levels and persistent stage IV hypertension in a nonvolume overloaded anephric patient

Z Vajo  1 , R A Moffitt, S Parvathala, B Szekacs, W D Dachman
Affiliations
Case Reports

Elevated endothelin-1 levels and persistent stage IV hypertension in a nonvolume overloaded anephric patient

Z Vajo et al. Am J Hypertens. 1996 Sep.

Abstract

Persistent hypertension after nephrectomy is in most cases due to increased fluid volume. Endothelin-1 is a potent endogenous vasoconstrictor peptide. Its role in the development and maintenance of hypertension is not completely understood, but it might be significant in some cases. We report a case of stage IV hypertension after nephrectomy with elevated endothelin-1 levels and no volume overload.

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