Neurogenesis in the adult rat: electron microscopic analysis of light radioautographs
- PMID: 887941
- DOI: 10.1126/science.887941
Neurogenesis in the adult rat: electron microscopic analysis of light radioautographs
Abstract
Three-month-old rats were injected intraperitoneally with [3H]thymidine (4.3 microcuries per gram of body weight) and allowed to survive for 30 days. Radioautography of 1-micrometer sections revealed labeled cells in the granular layers of dentate gyrus and olfactory bulb; these were confirmed as neurons by electron microscopy of reembedded 1-micrometer sections.
Similar articles
-
Neurogenesis in the 3-month-old rat visual cortex.J Comp Neurol. 1981 Jan 10;195(2):323-38. doi: 10.1002/cne.901950211. J Comp Neurol. 1981. PMID: 7251929
-
3H-thymidine-radiographic studies of neurogenesis in the rat olfactory bulb.Exp Brain Res. 1983;50(2-3):329-40. doi: 10.1007/BF00239197. Exp Brain Res. 1983. PMID: 6641865
-
RB and Cdc2 expression in brain: correlations with 3H-thymidine incorporation and neurogenesis.J Neurosci. 1993 Jul;13(7):2930-8. doi: 10.1523/JNEUROSCI.13-07-02930.1993. J Neurosci. 1993. PMID: 8331381 Free PMC article.
-
Adult Neurogenesis in Humans.Cold Spring Harb Perspect Biol. 2015 Jul 1;7(7):a018994. doi: 10.1101/cshperspect.a018994. Cold Spring Harb Perspect Biol. 2015. PMID: 26134318 Free PMC article. Review.
-
From progenitors to integrated neurons: role of neurotransmitters in adult olfactory neurogenesis.J Chem Neuroanat. 2011 Dec;42(4):304-16. doi: 10.1016/j.jchemneu.2011.05.006. Epub 2011 May 27. J Chem Neuroanat. 2011. PMID: 21641990 Review.
Cited by
-
The endogenous regenerative capacity of the damaged newborn brain: boosting neurogenesis with mesenchymal stem cell treatment.J Cereb Blood Flow Metab. 2013 May;33(5):625-34. doi: 10.1038/jcbfm.2013.3. Epub 2013 Feb 13. J Cereb Blood Flow Metab. 2013. PMID: 23403379 Free PMC article. Review.
-
Patterns of olfactory bulb neurogenesis in the adult zebrafish are altered following reversible deafferentation.Neuroscience. 2016 Sep 7;331:134-47. doi: 10.1016/j.neuroscience.2016.06.026. Epub 2016 Jun 23. Neuroscience. 2016. PMID: 27343831 Free PMC article.
-
Neurogenesis in the adult avian song-control system.Cold Spring Harb Perspect Biol. 2015 Jun 1;7(6):a019000. doi: 10.1101/cshperspect.a019000. Cold Spring Harb Perspect Biol. 2015. PMID: 26032719 Free PMC article. Review.
-
Matching Diabetes and Alcoholism: Oxidative Stress, Inflammation, and Neurogenesis Are Commonly Involved.Mediators Inflamm. 2015;2015:624287. doi: 10.1155/2015/624287. Epub 2015 May 7. Mediators Inflamm. 2015. PMID: 26063976 Free PMC article. Review.
-
The Interplay between the Hippocampus and Amygdala in Regulating Aberrant Hippocampal Neurogenesis during Protracted Abstinence from Alcohol Dependence.Front Psychiatry. 2013 Jun 27;4:61. doi: 10.3389/fpsyt.2013.00061. Print 2013. Front Psychiatry. 2013. PMID: 23818882 Free PMC article.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources