Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1996 Aug;4(8):1349-53.
doi: 10.1016/0968-0896(96)00123-x.

Synthesis and inhibitory properties of a thiomethylmercuric sialic acid with application to the X-ray structure determination of 9-O-acetylsialic acid esterase from influenza C virus

W Fitz  1 , P B Rosenthal, C H Wong
Affiliations

Synthesis and inhibitory properties of a thiomethylmercuric sialic acid with application to the X-ray structure determination of 9-O-acetylsialic acid esterase from influenza C virus

W Fitz et al. Bioorg Med Chem. 1996 Aug.

Abstract

2-alpha-Thiomethylmercuryl 9-acetamido-9-deoxy-sialoside was prepared and found to inhibit the 9-O-acetylsialic acid esterase from influenza C virus in a competitive manner with a Ki of 4.2 +/- 0.5 mM. The inhibitor is being used in the X-ray determination of the crystal structure of the esterase.

PubMed Disclaimer

Figures

None
Graphical abstract
See this image and copyright information in PMC

Similar articles

See all similar articles

Cited by

References

    1. Katagiri S., Ohizumi A., Homma M. J. Inf. Diseases. 1983;148:51. - PubMed
    2. Air G.M., Compans R.W. In: Genetics of Influenza Viruses. Palese P., Kingsbury D.W., editors. Springer; New York: 1983. Chap 9.
    1. Herrler G., Dürkop I., Becht H., Klenk H.D. J. Gen. Virol. 1988;69:839. - PubMed
    2. Formanowski F., Wharton S.A., Calder L.J., Hofbauer C., Meier-Ewert H. J. Gen. Virol. 1990;71:1181. - PubMed
    3. Herrler G., Klenk H.-D. Adv. Virus Res. 1991;40:213. - PMC - PubMed
    1. Monto A.S., Lim S.K. J. Inf. Diseases. 1974;129:271. - PMC - PubMed
    2. McIntosh K., Kapitkian A.Z., Turner H.C., Hartley J.W., Chanock R.M. Am. J. Epidemiol. 1970;91:585. - PMC - PubMed
    1. Zhang X., Kousoulas K.G., Storz J. Virol. 1992;186:318. - PMC - PubMed
    1. Vlasak R., Luytjes W., Spaan W., Palese P. Vol. 85. 1988. p. 4526. (Proc. Natl. Acad. Sci. U.S.A.). - PMC - PubMed

Publication types

MeSH terms

LinkOut - more resources