doi: 10.1016/0035-9203(77)90019-0.
Delayed hypersensitivity to PPD-S following BCG vaccination in African children--an 18-month field study
- PMID: 888171
- DOI: 10.1016/0035-9203(77)90019-0
Item in Clipboard
Delayed hypersensitivity to PPD-S following BCG vaccination in African children--an 18-month field study
Trans R Soc Trop Med Hyg.
1977.
Abstract
BCG vaccine given to young Gambian children produced a conversion rate, measured by delayed hypersensitivity to PPD-S, which increased with improving nutritional status. Retesting when nutrition had improved showed a considerable loss of delayed hypersensitivity in all nutritional groups. This may be the result of enhanced macrophage microbicidal acitvity at the time the BCG was administered. BCG is not likely to be very effective if given to malnourished children or to those who are undergoing repeated antigenic stimulation.
Similar articles
-
[Testing post-vaccination and post-infection hypersensitivity with the use of tuberculin PPD-S BCG Polska. I. Use of tuberculin PPD-S BCG in children vaccinated with BCG vaccine].Pneumonol Pol. 1982 Nov;50(11):599-607. Pneumonol Pol. 1982. PMID: 7182815 Polish. No abstract available.
-
Delayed hypersensitivity after BCG in preschool children in relation to their nutritional status.Indian J Med Res. 1981 Sep;74:392-8. Indian J Med Res. 1981. PMID: 7319578 No abstract available.
-
Tuberculin sensitivity in low birth weight and malnourished children.Indian Pediatr. 1995 Mar;32(3):354-7. Indian Pediatr. 1995. PMID: 8613293
-
Absence of association between delayed type hypersensitivity to tuberculin and atopy in children in The Gambia.Clin Exp Allergy. 2003 Jun;33(6):731-6. doi: 10.1046/j.1365-2222.2003.01599.x. Clin Exp Allergy. 2003. PMID: 12801305 Review.
-
BCG vaccination and the PPD test: what the clinician needs to know.J Fam Pract. 1995 Jan;40(1):76-80. J Fam Pract. 1995. PMID: 7807041 Review.
Cited by
-
Malnutrition and vaccination in developing countries.Philos Trans R Soc Lond B Biol Sci. 2015 Jun 19;370(1671):20140141. doi: 10.1098/rstb.2014.0141. Philos Trans R Soc Lond B Biol Sci. 2015. PMID: 25964453 Free PMC article. Review.
-
The immune system in children with malnutrition--a systematic review.PLoS One. 2014 Aug 25;9(8):e105017. doi: 10.1371/journal.pone.0105017. eCollection 2014. PLoS One. 2014. PMID: 25153531 Free PMC article.
-
BCG revaccination and tuberculin reactivity.Indian J Pediatr. 2001 Jan;68(1):21-5. doi: 10.1007/BF02728851. Indian J Pediatr. 2001. PMID: 11237231
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
