Review
The role of MCM/P1 proteins in the licensing of DNA replication
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- PMID: 8882583
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Review
The role of MCM/P1 proteins in the licensing of DNA replication
Trends Biochem Sci.
1996 Mar.
Abstract
The DNA replication licensing system ensures that eukaryotic chromosomes replicate precisely once per cell cycle. A central component of the licensing system, RLF-M, has recently been shown to consist of a complex of Mcm/P1 proteins. This result allows us to integrate data about the MCM/P1 family obtained in different eukaryotes, ranging from yeast to man, into a general picture of the way that chromosome replication is controlled.
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