[2 forms of UDPG-glycogen transferase in leukocytes of rabbit exudate in diabetes]

Abstract

UDPG-glycogen transferase existed mainly as D-form, depending on glucose-6-phosphate, and in minority as E-form in leukocytes of exudate of rabbits with diabetes and of control animals. The total enzymatic activity as well as the activity of D-form were almost the same both in leukocytes under diabetes and in control. The E-form activity accounted for 18% of the total enzymatic activity in leukocytes of diabetic rabbits and for 14% in leukocytes of control animals. Preliminary incubation of leukocyte homogenates at 37 degrees for 30 min led to decrease in the relation between the enzyme forms both in control rabbits and in animals with diabetes.