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Review
. 1996;19(4):548-52.
doi: 10.1007/BF01799115.

The role of magnetic resonance spectroscopy in the investigation of lactic acidosis and inborn errors of energy metabolism

D G Gadian  1 , J V Leonard
Affiliations
Review

The role of magnetic resonance spectroscopy in the investigation of lactic acidosis and inborn errors of energy metabolism

D G Gadian et al. J Inherit Metab Dis. 1996.

Abstract

Magnetic resonance spectroscopy (MRS) provides a non-invasive method of investigating disordered energy metabolism in vivo. Here, we briefly outline some MRS studies of skeletal muscle and brain metabolism that have been carried out in patients with inborn errors of energy metabolism. We concentrate in particular on the use of 1H MRS for the detection of elevated brain lactate in these patients.

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