Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comparative Study
. 1996 Sep;8(9):911-4.

Comparison of three urease tests for detection of Helicobacter pylori in gastric biopsy specimens

L Boyanova  1 , I Stancheva, D Todorov, R Kumanova, S Petrov, B Vladimirov, N Pehlivanov, R Mitova, I Chakarski, I Churchev
Affiliations
  • PMID: 8889460
Comparative Study

Comparison of three urease tests for detection of Helicobacter pylori in gastric biopsy specimens

L Boyanova et al. Eur J Gastroenterol Hepatol. 1996 Sep.

Abstract

Objective: To propose two modified urease tests for the detection of Helicobacter pylori in gastric biopsy specimens.

Patients and methods: The presence of H. pylori infection was determined in 237 patients undergoing upper gastrointestinal endoscopy. Three media were used for the urease tests: Christensen's 2% urea broth and two urea agar media, modified by increasing the concentration of urea (to 4% and 10%) and phenol red and omitting the nutrients.

Results: The modified tests had good sensitivity (> 78%), specificity (96%) and accuracy (> or = 86%) at 2 h using small amounts (15%) of biopsy homogenates. They were statistically more sensitive and accurate than Christensen's broth.

Conclusion: Both the modified 4% and 10% urea agar tests are simple, sensitive and specific and can be performed with small amounts of sample.

PubMed Disclaimer

Publication types

MeSH terms

LinkOut - more resources