This site needs JavaScript to work properly. Please enable it to take advantage of the complete set of features!

Skip to main page content

Add to Collections

Your saved search

Name of saved search:

Search terms:

Test search terms

Would you like email updates of new search results?

Yes
No

Email: (change)

Frequency:

Which day?

Which day?

Report format:

Send at most:

Send even when there aren't any new results

Optional text in email:

Your RSS Feed

Review

. 1996 Sep;36(9):792-8.

doi: 10.1002/j.1552-4604.1996.tb04252.x.

Inhibition of human cytochrome P450-3A isoforms by fluoxetine and norfluoxetine: in vitro and in vivo studies

D J Greenblatt¹, L L von Moltke, J Schmider, J S Harmatz, R I Shader

Affiliations

PMID: 8889899
DOI: 10.1002/j.1552-4604.1996.tb04252.x

Review

Inhibition of human cytochrome P450-3A isoforms by fluoxetine and norfluoxetine: in vitro and in vivo studies

D J Greenblatt et al. J Clin Pharmacol. 1996 Sep.

. 1996 Sep;36(9):792-8.

doi: 10.1002/j.1552-4604.1996.tb04252.x.

Authors

D J Greenblatt¹, L L von Moltke, J Schmider, J S Harmatz, R I Shader

Affiliation

¹ Department of Pharmacology and Experimental Therapeutics, Tufts University School of Medicine, Boston, MA 02111, USA.

PMID: 8889899
DOI: 10.1002/j.1552-4604.1996.tb04252.x

No abstract available

PubMed Disclaimer

Similar articles

Sertraline does not inhibit cytochrome P450 3A-mediated drug metabolism in vivo.
Preskorn SH, Alderman J, Greenblatt DJ, Horst WD. Preskorn SH, et al. Psychopharmacol Bull. 1997;33(4):659-65. Psychopharmacol Bull. 1997. PMID: 9493476
Venlafaxine and metabolites are very weak inhibitors of human cytochrome P450-3A isoforms.
von Moltke LL, Duan SX, Greenblatt DJ, Fogelman SM, Schmider J, Harmatz JS, Shader RI. von Moltke LL, et al. Biol Psychiatry. 1997 Feb 1;41(3):377-80. doi: 10.1016/s0006-3223(96)00406-4. Biol Psychiatry. 1997. PMID: 9024962 No abstract available.
Inhibition of terfenadine metabolism in vitro by azole antifungal agents and by selective serotonin reuptake inhibitor antidepressants: relation to pharmacokinetic interactions in vivo.
von Moltke LL, Greenblatt DJ, Duan SX, Harmatz JS, Wright CE, Shader RI. von Moltke LL, et al. J Clin Psychopharmacol. 1996 Apr;16(2):104-12. doi: 10.1097/00004714-199604000-00002. J Clin Psychopharmacol. 1996. PMID: 8690825
Serotonin selective reuptake inhibitor drug interactions and the cytochrome P450 system.
Ereshefsky L, Riesenman C, Lam YW. Ereshefsky L, et al. J Clin Psychiatry. 1996;57 Suppl 8:17-24; discussion 25. J Clin Psychiatry. 1996. PMID: 8698676 Review.
Antidepressant drug interactions and the cytochrome P450 system. The role of cytochrome P450 2D6.
Ereshefsky L, Riesenman C, Lam YW. Ereshefsky L, et al. Clin Pharmacokinet. 1995;29 Suppl 1:10-8; discussion 18-9. doi: 10.2165/00003088-199500291-00004. Clin Pharmacokinet. 1995. PMID: 8846618 Review.

See all similar articles

Cited by

Metabolism and pharmacokinetics of selective serotonin reuptake inhibitors.
DeVane CL. DeVane CL. Cell Mol Neurobiol. 1999 Aug;19(4):443-66. doi: 10.1023/a:1006934807375. Cell Mol Neurobiol. 1999. PMID: 10379420 Free PMC article. Review.
Effect of SSRI exposure on the proliferation rate and glucose uptake in breast and ovary cancer cell lines.
Stapel B, Melzer C, von der Ohe J, Hillemanns P, Bleich S, Kahl KG, Hass R. Stapel B, et al. Sci Rep. 2021 Jan 13;11(1):1250. doi: 10.1038/s41598-020-80850-9. Sci Rep. 2021. PMID: 33441923 Free PMC article.
Clinical pharmacokinetics of reboxetine, a selective norepinephrine reuptake inhibitor for the treatment of patients with depression.
Fleishaker JC. Fleishaker JC. Clin Pharmacokinet. 2000 Dec;39(6):413-27. doi: 10.2165/00003088-200039060-00003. Clin Pharmacokinet. 2000. PMID: 11192474 Review.
Getting the balance right: Established and emerging therapies for major depressive disorders.
Perović B, Jovanović M, Miljković B, Vezmar S. Perović B, et al. Neuropsychiatr Dis Treat. 2010 Sep 7;6:343-64. doi: 10.2147/ndt.s10485. Neuropsychiatr Dis Treat. 2010. PMID: 20856599 Free PMC article.
An Interesting Case of Carbamazepine-Induced Stevens-Johnson Syndrome.
Masuka JT, Muzopambwa G, Khoza S, Chibanda D. Masuka JT, et al. Drug Saf Case Rep. 2018 Dec 10;6(1):1. doi: 10.1007/s40800-018-0095-y. Drug Saf Case Rep. 2018. PMID: 30535610 Free PMC article.

See all "Cited by" articles

Publication types

Actions
Actions
Actions
Actions

MeSH terms

Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions

Substances

Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions

Grants and funding

etc

LinkOut - more resources

Full Text Sources
- Ovid Technologies, Inc.
- Wiley