doi: 10.1016/0002-9378(79)90938-4.
Human fibroblasts produce "pregnancy-specific" beta-1 glycoprotein in vitro
- PMID: 88900
- DOI: 10.1016/0002-9378(79)90938-4
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Human fibroblasts produce "pregnancy-specific" beta-1 glycoprotein in vitro
Am J Obstet Gynecol.
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Abstract
Normal and genetic variant strains of nonmalignant human fibroblasts produce in vitro a substance indistinguishable from the recently described "pregnancy-specific" beta-1 glycoprotein (PSbetaG, PAPP-C, SP1). Demonstration of this presumed placenta-specific material in a nonplacental site raises questions about its normal physiologic role and use as a cancer marker.
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