Review
Molecular basis of T lymphocyte CD4 antigen functions
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- PMID: 8891524
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Review
Molecular basis of T lymphocyte CD4 antigen functions
Eur J Clin Chem Clin Biochem.
1996 Sep.
Abstract
The T cell surface antigen CD4 plays a pivotal role in the MHC class II-restricted response of specific T lymphocytes and serves as the major receptor of human immunodeficiency viruses (HIV). Recent studies have shown the high complexity of CD4 functions in physiological and pathological conditions. We report here a short review of recent developments in the field and discuss the structural features which regulate the functions mediated by the CD4 coreceptor in mature T lymphocytes.
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