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Review
. 1996 Aug;38(4):291-6.
doi: 10.1007/s00282-996-0291-6.

Clonal chromosome abnormalities in Fanconi anemia

R Berger  1 , P Jonveaux
Affiliations
Review

Clonal chromosome abnormalities in Fanconi anemia

R Berger et al. Hematol Cell Ther. 1996 Aug.

Abstract

Fanconi anemia (FA) belongs to the chromosomal instability syndromes and frequently evolves toward hematopoietic malignancy. While the recent isolation of one of the genes of FA allows to view to gene therapy, the best treatment is currently bone marrow transplantation. In this review, the data on clonal chromosome abnormalities of FA patients are presented and their significance discussed in the context of the disease.

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