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. 1996 Nov;178(21):6366-8.
doi: 10.1128/jb.178.21.6366-6368.1996.

Role of the two-component signal transduction and the phosphoenolpyruvate: carbohydrate phosphotransferase systems in competence development of Haemophilus influenzae Rd

M L Gwinn  1 , D Yi, H O Smith, J F Tomb
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Role of the two-component signal transduction and the phosphoenolpyruvate: carbohydrate phosphotransferase systems in competence development of Haemophilus influenzae Rd

M L Gwinn et al. J Bacteriol. 1996 Nov.

Erratum in

  • J Bacteriol 1997 Jan;179(2):567

Abstract

Haemophilus influenzae Rd becomes competent for transformation by nutritional downshift or transient anaerobic growth through a process that requires cyclic AMP receptor protein and adenylate cyclase. Insertion mutations in crr or ptsI of the phosphoenolpyruvate:carbohydrate phosphotransferase system lowered transformation frequencies, and the effect was reversed by the addition of cyclic AMP. However, insertions into H. influenzae homologs of two-component signal transduction genes had no effect on competence.

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